
There are eight primary causes of neurotransmitter deficiency, imbalance and disruption:
1. Alcohol, mind-altering drugs and nicotine (This includes both recreational and prescription based. Including marijuana, cocaine, heroin, benzodiazepines, amphetamines, anti-depressants etc.)
Alcohol and drugs are a catch 22. Many people with neurotransmitter imbalances or deficiencies often turn to alcohol and drugs to counteract or soothe the symptoms they are having from an already existing imbalance or deficiency and although initially they provide some relief, they ultimately damage and deplete neurotransmitters even more. Anyone with neurotransmitter issues is at extremely high risk of addiction. On the other hand, the use of drugs and alcohol cause neurotransmitter depletion as they overstimulate them to the point that the brain stops producing them.
2. Diet
Sugar and caffeine are the two most detrimental foods for neurotransmitters, because they have a similar effect on the brain as hard drugs, but so is white flour and other refined junk food. A diet that is low in protein or high in complex carbohydrates is also a major contributor. Follow this link to our Daily Nutrition page for information on healthy eating
3. Environmental toxins
Common everyday chemicals found in most peoples homes like perfume, cologne, cleaning supplies, air fresheners, housing construction, personal care products, carpeting, pesticides, herbicides, nail polish, laundry soap, fabric softener, clothing etc., have a serious impact on neurotransmitters, because they can land on receptors and/or inhibit production. Read more on how toxic our world is here.
4. Chronic stress
High levels of ongoing stress also cause malfunctioning and depletion of neurotransmitters. This can be the result of a high stress lifestyle that doesn’t ease up or stressful circumstances you must endure like a demanding job, poverty, dysfunctional relationships, abuse, violence, chronic illness etc.
If you lived with child abuse or neglect as a child, chances are very great that your neurotransmitters are out of balance and/or deficient. The same applies to prisoners of war, victims of violence, victims of a natural disaster, civilians living in a war zone, and war veterans. For example, PTSD is the result of neurotransmitter disruption. Read more on the effects stress has on the body – here.
5. Genetics
Some people are born without certain enzymes that are needed to synthesize neurotransmitters which results in deficiencies or disruption ofof neurotransmitters.
6. Nutritional deficiencies
Adequate levels of vitamins, minerals, amino acids, and fatty acids are crucial for the production and regulation of neurotransmitters. As much as 80% of the population has nutritional deficiencies. Amino acid deficiencies is the primary nutrient needed for the production of neurotransmitters as well as healthy fats. Amino acid deficiencies are extremely common because they are derived from protein and most of the population is not eating enough protein. To ensure sufficient intake of clean protein – follow this link.
7. Candida overgrowth
The overgrowth of Candida yeast is extremely common in our society and it too alters and disrupts the functioning of neurotransmitters. Other unfriendly organisms like bacteria and parasites may interfere in neurotransmitter function as well.
8. Food allergies and sensitivities
Undiagnosed food allergies and sensitivities can inhibit or stimulate neurotransmitter activity. Read more on Food Allergies & Intolerances – here.
Source: Holistic Help.net

