The “RNA Disposition” Cancer Theory


In order to develop an understanding of the theory behind Dr. McDonald’s approach to cancer and to make use of our Protocols and treatments, one needs to keep an open mind and allow scientific fact, where presented, to be the basis of this theory.  Changes or mutations to the DNA, or oncogenes have always been understood to be the cause of cancer.  However, Dr. McDonald postulates that any and all damage to cells is a critical determining factor in the cause of cancer and that factors outside the nucleus are responsible for determining the character of the cell. Before we begin making suggestions and recommendations as to the best way to treat your dis-ease utilizing UNA3 and various protocols we have adapted over the years to assist us in this war – we would like to give you an insight into what cancer is, how it starts and some common causes as seen by Dr. McDonald.

The human cell consists of

Nucleus: The Command and Control centre of the cell and DNA Archives. The nucleus is also seen as the cell producing facility that replicates exact copies of DNA.

Nucleolus:  The RNA factory where the production of ribosomal RNA manufactures up to 10,000 ribosomes per minute.

Mitochondria:  This is the energy factory (or the electricity generator) of each cell that produces ATP and ADP through a process known as the Krebs (Citric acid) cycle. The mitochondrion combines sugars and fats with oxygen to yield adenosine triphosphate (ATP) and water producing 95% of the energy that a cell needs to function. Co-enzyme Q10 is used as an essential catalyst for ATP production and Acetyl CoA is produced at the start of the citric cycle for the synthesis of fatty acids and metabolism of carbon sugars. The Krebs cycle makes use of Malic, Fumaric and citric acids in the biosynthesis and oxidation of other molecules, producing ATP and ADP, sending the energy into the outer membrane to be used in the body.

Telomerase: is the enzyme that governs longevity (regulator of the telomere) of the cells.

Telomere: This is the tail end of the chromosomes that protect the DNA.  Cell division shortens the length of the telomere and upon reaching critical length; the cell is unable to divide any further and dies. The length of the telomere is determined by loss and addition of base pairs. Cell division causes loss and the telomerase is responsible for addition. 

p53 Gene: The p53 gene’s proteins have three functions: activate DNA repair, induce growth arrest upon recognition of DNA damage (for DNA repair) or initiate cell apoptosis.  The p53, based in the nucleus, controls and protects the entire cell and responds to cellular stress. The choice of function is influenced by various factors, including what type of cell it is. When a cell is damaged, two major cell death pathways can be followed: Extrinsic where the caspase cascade activation is triggered by the BAX gene, or Intrinsic, where the mitochondrial pathway shifts the balance in the Bcl2 family towards the pro-apoptotic members.

Bax Gene: is central to cell apoptosis and is belongs to the BCL2 family. It is a weapon gene which will cause loss of membrane potential, creating an opening in the mitochondrial voltage to release cytochrome C, which in turn activates the release of caspase 3 which leads to cell death. This command comes from the p53 gene. (The function can be compared to a needle that pierces a hole in the mitochondria, releasing cytochrome C, activating the release of CASP3, which results in the dissolving of the cell) When BAX predominates, programmed cell death is accelerated, and the death repressor activity of the Bcl2 gene is countered.

BcL2: B-cell leukaemia 2 – the mitosis protein – controls the apoptosis (shedding) of the outer membrane of the cell by suppressing the apoptosis and preventing activation of caspases that carry out the apoptotic process.

Cancers vary in pH levels and for the sake of easy reading examples are used, but on in-depth study one can differentiate to many different levels and detail of the pH of cancers.

pH6.5 cancers: (variations of different cancer tumour pH’s range between 5.66 to 7.78) These cancers are detectable in the blood and occur when the mitochondria and/or cell outer membrane is damaged, thereby activating the p53 gene to halt cell activity whilst inspecting the damage.  When the Krebs cycle is not active or does not supply sufficient energy to cells, the muscle cells and cancer cells will make use of the Cori cycle to energise them. This happens through the fermentation of glycogen into lactic acid, which is sent to the liver, converted to glucose and returned to the cell. The process is called glyconeogenesis. It is highly energy intensive, requiring 6ATP equivalents per glucose formed. A cancer cell makes use of the Cori system to sustain its life and function, should the mitochondria not receive the message from the p53 to activate the Bax gene for self-destruction with the cancerous results that become visible in tests.

Blood test results from patients suspected of having a pH6.5 cancer will indicate following:

  • White cell increase
  • CA markers increase
  • Platelet reduction

pH8 cancers: cannot be detected by blood tests as the pH level of the cancer cells are similar to that of the body’s, which ranges between pH7.5 to pH8.  In order to flourish, this type of cancer usually taps directly into the vascular system or one of the organs. During the process of cell division, if any damage should occur to the outer membrane of the cell, the P53 gene responsible for suspending the cell cycle until the damage can be repaired, freezes the function of the telomerase and not that of the telomere, resulting in the telomere continuing its cell division uninterrupted.  This process of unrestrained reproduction of damaged DNA, if in a vicinity of a direct food source, results in the development of cancer tumours that are usually detected too late.  The late detection is as a result of the mitochondria function appearing normal, the Krebs cycle continuing undisturbed and the P53 gene remaining frozen thereby not ensuring normal cell apoptosis.

 Dr. McDonald postulates that his explanation on Cell Biology linked to his RNA Disposition  Cancer Theory purports that other than the exact locations and comparison of components and organs and what they become (which is as close to our theory as makes sense, the purpose and locations could vary), in order to allow the reader to gain an understanding of this theory he has supplied the following explanation stating that what originated from the RNA actually becomes a human being, and whatever was in the original program, once enlarged, has a place and function in the human body.

Cell biology

When the RNA is enlarged, it would be the size of a pin prick. When enlarged further a cell would appear.

Enlarged further an entire human body would appear

Then the following would be detected:

  • The Nucleolus represents the Brain
  • The Nucleus becomes the Small Brain
  • The Telomerase becomes the Pituitary
  • The p53 represents the Pineal Gland
  • The Telomere becomes the Reproductive System
  • The BCL2 and Bax Genes become the Heart / Upper and Lower Chambers
  • The Mitochondria becomes the v=Vascular System / blood working with internal organs
  • The Peroxisome is the Liver
  • The Golgi Apparatus represents the Thymus
  • The Lysosome become the Stomach and Pancreas
  • The Cilia are the Lungs
  • The Microtubules become the Intestines
  • The centriole becomes the Kidneys
  • The Cytoskeleton is the skeletal bone structure
  • The endoplasmic Reticulum will be the muscles

Some Causes of Cancer

At cellular level, damage to the cell membrane can be caused by:

  1. Incorrect diagnosis and treatment of diseases
  2. A white blood cell creating a hole in the cell membrane due to the surface being pH5.  (White blood cells are programmed to destroy pathogens with a pH level of 5.  The most plausible reason for the cell pH changing from pH 7.5 to pH 5 would be as a result of biological or chemically induced changes by products such as sodium benzoate, which is used as a preservative in food coming into contact with vitamin C (ascorbic acid). Combined a carcinogenic benzene is created, which upon touching a cell, alters the pH 7.5 to pH 5, causing the immune system to damage or destroy an otherwise healthy cell.
  3. Chemotherapy or radiation damage
  4. Surgical damage
  5. Pathogen or viral damage
  6. Fungi
  7. Excessive cell mitosis
  8. The RNA Disposition.

There are thousands more reasons but all damage to the membrane will cause a ripple effect, which results in various cancers occurring in different areas of the body. These cancers once detected are usually acknowledged to have been present in the body for a minimum of eight years.

Types of Cancer – Simplified

  • Carcinoma – a tumour derived from epithelial cells, those cells that line the surface of our skin and organs.  Our digestive tract and airways are also line with epithelial cells.  This is the most common cancer type and represents approximately 80% to 90% of all cancers reported
  • Sarcoma – a tumour derived from muscle, bones, cartilage, fat or connective tissues
  • Leukemia – a cancer derived from white blood cells or their precursors.  The cells that form both red and white blood cells are located in the bone marrow.
  • Lymphoma – a cancer of bone marrow derived cells that affect the lymphatic system
  • Myeloma – a cancer involving the white blood cells responsible for the production of antibodies (B-lymphocytes or B-cells)

Studies show that there are approximately 26 areas in the body that are commonly diagnosed with various types of cancer.  Evolving from this is the reference system used by oncologists (ICD10 codes) that present a total of 488 areas and types of cancers that are covered by medical aid.

The RNA Disposition theory proposes that the body is usually always able to repair itself, given the right conditions and that in the event the body is unable to do so, one should look to treating the person holistically, as opposed to just treating the disease. 

Dr. McDonald’s cancer theory of The RNA Disposition not only theorises that all damage to cells lead to cancer, but also postulates that the causes of damage to these cells can be brought about by any of the six senses: Taste, Touch, Sound, Sight, Smell and Thought. The disposition of the RNA is postulated to a strong mind/body connection, wherein the state of the patients mind and thought processes will influence the character of the cells of the RNA Sir1, 2, 3 and 4 function, which leads to a disruption of the telomerase signalling pathway.

Dr. McDonald’s RNA Disposition Cancer Theory is firmly grounded in the “The Mind/Body Connection” and is a theory that has been postulated by both Doctor and Scientist alike for some time.  However, the mechanism behind The Mind/Body Connection was recently confirmed.

UCLA scientists found that the stress hormone cortisol suppresses the immune cells’ ability to activate the telomerase.  This may explain why the cells of persons under chronic stress have shorter telomeres.

Immune cells (stained blue) end in protective caps called telomeres (stained yellow) that are shorter in the elderly — and in persons suffering chronic stress. A new UCLA study suggests cortisol is the culprit behind premature aging of the immune system in stressed-out people. (Credit: UCLA/Effros lab)

Every cell has a “sell-by-date” called a telomere.  This telomere is shortened each time the cell divides and it is this shortened telomere that is linked to a range of human diseases.  Previous studies show that an enzyme within the cell, called telomerase, kept immune cells young by preserving their telomere length and ability to continue dividing.  The study further reveals that stress makes people susceptible to illness, especially those persons subjected to long-term stress such as air traffic controllers, astronauts, soldiers and people who make long daily commutes to and from home.

Rita Effros (Professor of pathology and laboratory medicine at the David Geffen School of Medicine at UCLA and a member of the Jonson Cancer Centre, Molecular Biology Institute and UCLA AIDS Institute), states that when a body is under stress, it boosts production of cortisol to support a “fight or flight” response.  If this hormone remains elevated in the bloodstream for long periods of time, it wears down the immune system.

When a lay person pictures the function of the brain an image of the brain with a network of nerves comes to mind.  Believing that it is this network of nerves that co-ordinates the body’s responses to stimuli.  However, Dr. McDonald stipulates that it is “master gland” or pituitary which regulates the body’s processes.

In 1940 Scharrer & Scharrer discovered and documented that some neural cells were able to produce hormones and that certain neurons within the hypothalamus of the brain convert the neural impulses of the mind into the hormonal information substance of the body. 

In 1969 Wurtman and Anton-Tay termed this conversion process of neuronal signals into messenger molecules as neuro-endocrinal transduction.  It is from this point on that the more general concept of information transduction into today’s psychobiological theories evolved.

The area of sensory-perceptual psychology is the most familiar example of information transduction where information in the form of light is transduced into chemical information and is encoded by the rhodopsin molecules in the eye’s retina.

Rhodopsin transduces this chemical information into neural information via the “bipolar” and ganglion cells within the retina which in turn transmits the neural information through the optic nerve to the visual association cortex of the brain.

The analogous process of information transduction by sensory-perceptual systems at this level of mind-body communication was used to update Hans Selye’s theory of stress and the General Adaptation Syndrome as the basis of psychosomatic medicine (Rossi, 1986c d; Rossi & Ryan, 1986). Selye’s life work demonstrated that there were three routes, channels, or systems by which mental stress was transmitted into the body’s “psycho-somatic” responses: the autonomic, endocrine, and immune systems.

The limbic-hypothalamic-pituitary system of the brain plays the major integrative role in the mind modulation of all three of these major systems, as it is the major mind-body information transducer. This is where the translator between the languages of the mind (in the forms of sensation, imagery, verbal language, etc.) and the languages of the body (information substances such as neuropeptides, hormones, immunotransmitters, etc.) take place. 

Dr. McDonald supports “The Cellular-Genetic Connection” which discusses the mind-gene-molecule communication network and the body’s classic psychosomatic responses to stress as well as Rossi’s theory that a mind-gene healing operon exists.  

A short quote from Rossi’s work:  “…The mind-body-gene information loops usually operate at an ‘unconscious’ level.

Dr. McDonald’s postulation that even at a cellular level the body is designed and programmed to learn.  So, for example if one were exposed to radiation – magnetic or electrical energy, (such as Telkom or cell phone towers), as a defence mechanism, the mind body-connection often creates a link between the conscious and subconscious mind and put plans in place to protect itself. The conscious mind knowing you live there permanently, would then subconsciously make the mind/body connection which in turn causes ones body that is currently under extreme stress caused by this electrical energy could create either skin, brain or lung cancer. It has been Dr. McDonald’s experience that once the person moves away from this source of electrical/magnetic energy, the cancer often dies.

Dr. McDonald points out that people with good emotional health are aware of their thoughts, feelings and behaviours and as a result, they have learned healthy ways to cope with the stress and problems that are a normal part of life. This type of person usually feels good about themselves and they have healthy relationships.

However, many things that happen in your life can disrupt your emotional health and lead to strong feelings of sadness, stress or anxiety.    “Good” changes can be just as stressful as “bad” changes.  Your body responds to the way you think, feel and act. This is the “mind/body connection.” When you are stressed, anxious or upset, your body tries to tell you that something isn’t right. For example, high blood pressure or a stomach ulcer might develop after a particularly stressful event, such as the death of a loved one.   As discussed it is this poor emotional health that can weaken your body’s immune system and this weakened immune system can lead to innumerable health issues.

In order to ensure that you control this emotional rollercoaster, one should try to recognize ones emotions and understand why one is having them. Sorting out the causes of sadness, stress and anxiety in ones life can help will help you to manage your emotional health.  Ensure that you express your feelings in appropriate ways. If feelings of stress, sadness or anxiety are causing physical problems, keeping these feelings inside can make you feel worse.

Live a balanced life. Try not to obsess about the problems at work, school or home that lead to negative feelings. This doesn’t mean you have to pretend to be happy when you feel stressed, anxious or upset. It’s important to deal with these negative feelings, but try to focus on the positive things in your life too. Research has shown that having a positive outlook can improve your quality of life and give your health a boost. You may also need to find ways to let go of some things in your life that make you feel stressed and overwhelmed. Make time for things you enjoy.

Develop resilience. People with resilience are able to cope with stress in a healthy way. Resilience can be learned and strengthened with different strategies. These include having social support, keeping a positive view of yourself, accepting change, and keeping things in perspective.  

Calm your mind and body. Relaxation methods, such as meditation, are useful ways to bring your emotions into balance. Meditation is a form of guided thought. It can take many forms. For example, you may do it by exercising, stretching or breathing deeply. Ask your family doctor for advice about relaxation methods. 

Take care of yourself. To have good emotional health, it’s important to take care of your body by having a regular routine for eating healthy meals, getting enough sleep and exercising to relieve pent-up tension. Avoid overeating and don’t abuse drugs or alcohol.

Our aims with the protocols we have established for fighting this war If the cancer is pH 6.5 or pH 8, at cellular level our aim is to:

  • Restart the Krebs Cycle and restore it to its normal state and/or to activate the Bax Gene for the cell to self-destruct
  • Unfreeze the p53 gene so that the cell can return to normal function and the normal cycle of apoptosis is activated
  • Stimulate the nucleolus to forget the memory of the attack, which caused the damage to the cell in the first place.

When the damage is done to the whole organ or the cancer is in the entire organ, it would not be possible to do reach our aims as set out above.

This being the case, our new goal would be to find the cause of the cancer and eliminate it by using the 6 senses protocol and ensuring a permanent change of conditions, which the RNA can believe.


  • Factors that cause damage to the outer cell membrane range from 1 to 1 million but they are factors and not cancer.  Cancer is a disease caused by an unhappy RNA (intelligence) and the causes must be looked at. 
  • Anger or aggression (chemo or radiation) is never the answer as it will aggravate the RNA and make it totally immune on one onslaught only.
  • Wrong diagnoses / treatments are also detrimental.
  • Treating cancers that have not been exposed to radiation or chemo results in a 90% success rate, but treating cancers that have been exposed have a 97% fatality rate.  Over exposure to chemo results in all red blood cells being destroyed and ultimately the cancer spreads to the liver, which results in a 99% fatality rate due to organ failure from chemo damage.  Radiation kills the CD4 (white blood cells) or immune system and as a result, the body is exposed to any opportunistic pathogen and virus resulting in early death similar to AIDS.


It would be ideal to have your health care practitioner, spiritual advisor, psychologist, best friend, homeopath, naturopath and nutritionist present when trying to diagnose and treat cancer, as all would have beneficial contributions to make. To study the market for different cures is advisable but once the chemo or radiation route has been followed, the success rate is drastically reduced.

So, what is the future of this theory one might ask? 

Whilst visual proof and an exceptionally good recovery record in patients making use of the alternative approach to cancer treatment, as set out by Dr. McDonald, is evident and on record, additionally conducted experimental verification would be required by the medical fraternity, wherein the effects of the RNA Disposition theory on cancer treatment is documented for analysis, before this approach would ever find favour with doctors before they no longer make use of the controlled medical-industrial and turnover based treatments such as chemo or radiation.  However, in the final analysis, the positive results obtained in cancer patients having used these protocols far outweigh the need for profit, and is well supported by those with an open mind and a care for the needs of others.